Calcimimetics
from class: Pharmacology for Nurses Definition Calcimimetics are drugs that mimic the action of calcium on tissues, particularly by binding to and activating the calcium-sensing receptors (CaSR) on the parathyroid gland. This leads to a decrease in parathyroid hormone (PTH) secretion.
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Predict what's on your test 5 Must Know Facts For Your Next Test Calcimimetics are used primarily to treat secondary hyperparathyroidism in patients with chronic kidney disease. They work by increasing the sensitivity of the calcium-sensing receptors on the parathyroid gland to extracellular calcium. Cinacalcet is a commonly prescribed calcimimetic drug. By reducing PTH levels, calcimimetics help manage bone metabolism and serum calcium levels in affected patients. Side effects can include hypocalcemia, nausea, and vomiting. Review Questions What is the primary use of calcimimetics in clinical practice? How do calcimimetics affect parathyroid hormone (PTH) secretion? Name a commonly prescribed calcimimetic drug.
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