Pharmacology for Nurses

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Buprenorphine

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Pharmacology for Nurses

Definition

Buprenorphine is a partial opioid agonist used to treat opioid use disorder. It helps reduce withdrawal symptoms and cravings without producing the same high as full opioids.

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5 Must Know Facts For Your Next Test

  1. Buprenorphine has a ceiling effect, limiting its potential for misuse.
  2. It can be prescribed in various forms, including sublingual tablets and films.
  3. Buprenorphine is often combined with naloxone to prevent misuse by injection.
  4. Healthcare providers need special training and certification to prescribe buprenorphine for opioid use disorder.
  5. Common side effects include headaches, insomnia, sweating, and constipation.

Review Questions

  • What is the mechanism of action of buprenorphine in treating opioid use disorder?
  • Why is buprenorphine often combined with naloxone in treatment formulations?
  • What are some common side effects of buprenorphine?
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