Macrophages

Definition

Macrophages are immune cells that play a critical role in detecting, engulfing, and destroying pathogens and apoptotic cells. They are essential for maintaining tissue homeostasis and orchestrating inflammatory responses, especially in the lungs.

5 Must Know Facts For Your Next Test

1. Macrophages are involved in the inflammatory response seen in chronic pulmonary illnesses like COPD and asthma.
2. They secrete cytokines that can exacerbate inflammation in the lungs.
3. Macrophages help clear out dead cells and debris from the lung tissue, which is crucial for patients with pulmonary conditions.
4. Dietary nutrients such as omega-3 fatty acids can modulate macrophage activity, potentially reducing lung inflammation.
5. Antioxidants found in certain foods may enhance macrophage function, aiding in better respiratory health.

Review Questions

• What role do macrophages play in chronic pulmonary illnesses?
• How can dietary nutrients affect macrophage activity?
• Why is it important for macrophages to clear dead cells and debris from lung tissue?

Related terms

Cytokines: Small proteins released by cells that have a specific effect on cell-to-cell communication and behavior of other cells.

COPD:

Chronic Obstructive Pulmonary Disease characterized by long-term breathing problems and poor airflow.

Omega-3 Fatty Acids:

Essential fats commonly found in fish oils that have anti-inflammatory properties.