key term - Angiotensinogen

Definition

Angiotensinogen is a precursor protein produced by the liver that plays a critical role in blood pressure regulation and fluid balance in the body. It is converted into angiotensin I by the action of renin, an enzyme released by the kidneys.

Related terms

Renin:

An enzyme secreted by the kidneys that converts angiotensinogen into angiotensin I, starting the process of blood pressure regulation.

Angiotensin II:

A potent vasoconstrictor formed from angiotensin I through the action of ACE (angiotensin-converting enzyme), responsible for narrowing blood vessels and raising blood pressure.

Aldosterone: A hormone stimulated by angiotensin II that increases sodium retention and potassium excretion by the kidneys, contributing to increased water retention and blood volume