Renin is an enzyme secreted by the juxtaglomerular cells of the kidneys in response to low blood pressure or decreased sodium chloride concentration. It plays a critical role in the body's regulation of blood pressure, electrolyte balance, and fluid volume.
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A potent vasoconstrictor formed from angiotensin I through the action of angiotensin-converting enzyme (ACE), primarily involved in blood pressure regulation and stimulated by renin activity.
Aldosterone: A hormone secreted by the adrenal glands that increases sodium reabsorption in the kidneys, whose secretion is partly regulated by angiotensin II, stimulated by renin