Apoptosis

Definition

Apoptosis is the process of programmed cell death that occurs in multicellular organisms. It is a crucial mechanism for maintaining cellular health and homeostasis.

5 Must Know Facts For Your Next Test

1. Apoptosis plays a key role in eliminating infected cells and can be induced by anti-infective drugs.
2. It is distinct from necrosis, which is uncontrolled cell death resulting from injury.
3. In Alzheimer's disease, abnormal apoptosis may contribute to neuronal cell loss.
4. Certain antibiotics can trigger apoptosis in bacterial cells as part of their mechanism of action.
5. Antiviral and antifungal drugs may also exploit apoptotic pathways to eliminate infected cells.

Review Questions

• What role does apoptosis play in the effectiveness of anti-infective drugs?
• How does apoptosis differ from necrosis?
• Why is apoptosis significant in the context of Alzheimer's disease?

Related terms

Necrosis:

Uncontrolled cell death due to injury or infection.

Cell Homeostasis: The balance of cell proliferation and death to maintain tissue stability.

Neurodegeneration:

The progressive loss of structure or function of neurons, often associated with diseases like Alzheimer's.