Adrenal insufficiency

Definition

Adrenal insufficiency is a condition where the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol. It can impact various bodily functions, including stress response and inflammation control.

5 Must Know Facts For Your Next Test

1. Corticosteroids are commonly prescribed to manage adrenal insufficiency by replacing deficient hormones.
2. Symptoms of adrenal insufficiency include fatigue, muscle weakness, and low blood pressure.
3. Adrenal crisis is a severe complication that can occur if adrenal insufficiency is not properly managed and requires immediate medical intervention.
4. Long-term use of corticosteroids for treating lower respiratory disorders can suppress natural adrenal function, potentially leading to secondary adrenal insufficiency.
5. Hydrocortisone is often the drug of choice for cortisol replacement in patients with adrenal insufficiency.

Review Questions

• What role do corticosteroids play in managing adrenal insufficiency?
• What are some common symptoms associated with adrenal insufficiency?
• Why might long-term corticosteroid use lead to secondary adrenal insufficiency?

Related terms

Corticosteroids:

A class of steroid hormones used to reduce inflammation and manage conditions like asthma.

Hydrocortisone:

A synthetic corticosteroid used as a replacement therapy in patients with insufficient cortisol production.

Adrenal Crisis: A life-threatening condition requiring emergency treatment due to severely low levels of cortisol.