Acitretin

Definition

Acitretin is an oral retinoid used primarily to treat severe psoriasis. It works by modulating the growth of skin cells.

5 Must Know Facts For Your Next Test

1. Acitretin is a derivative of Vitamin A and is taken orally.
2. It is often prescribed for severe, resistant, or disabling forms of psoriasis.
3. Patients taking Acitretin should avoid alcohol due to the risk of forming a metabolite that can persist in the body for prolonged periods.
4. Women of childbearing potential must use effective contraception during treatment and for at least three years after discontinuing Acitretin due to its teratogenic effects.
5. Common side effects include dry skin, lips, and eyes; liver enzyme abnormalities; and increased lipid levels.

Review Questions

• What are the primary indications for prescribing Acitretin?
• Why must patients avoid alcohol when taking Acitretin?
• What precautions must women of childbearing potential take when using Acitretin?

Related terms

Psoriasis:

A chronic autoimmune condition that causes rapid skin cell turnover resulting in scaling and inflammation.

Retinoids:

A class of compounds derived from Vitamin A used in dermatology to regulate epithelial cell growth.

Teratogenicity:

The capability of a drug or substance to cause birth defects.