Lipase

Definition

Lipase is an enzyme that catalyzes the breakdown of fats into glycerol and free fatty acids. It is essential for the proper digestion and absorption of dietary lipids in the small intestine.

5 Must Know Facts For Your Next Test

1. Lipase is primarily produced by the pancreas and secreted into the small intestine.
2. It plays a crucial role in converting triglycerides into monoglycerides and free fatty acids.
3. Lipase activity is influenced by bile salts, which emulsify fats to increase surface area for enzyme action.
4. Deficiency in lipase can lead to malabsorption disorders, such as steatorrhea, where fats are improperly digested.
5. In addition to pancreatic lipase, there are other types like gastric and lingual lipase that initiate fat digestion earlier in the digestive tract.

Review Questions

• Where is lipase primarily produced and what is its main function?
• How do bile salts affect the activity of lipase?
• What condition might result from a deficiency in lipase?

Related terms

Amylase:

An enzyme that breaks down starches into sugars during digestion.

Bile Salts: Compounds produced by the liver that aid in the emulsification of fats for easier digestion.

Protease: An enzyme that breaks down proteins into peptides and amino acids in the digestive system.