Hematopoiesis

Definition

Hematopoiesis is the process of forming new blood cells in the body, including red blood cells, white blood cells, and platelets. It primarily occurs in the bone marrow and is essential for maintaining healthy blood function throughout life.

5 Must Know Facts For Your Next Test

1. Nutrients such as iron, vitamin B12, folate, and vitamin C are critical for effective hematopoiesis.
2. Hematopoietic stem cells (HSCs) in the bone marrow differentiate into various types of blood cells.
3. Iron deficiency can lead to impaired hematopoiesis and result in anemia.
4. Vitamin B12 and folate deficiencies can cause megaloblastic anemia due to ineffective hematopoiesis.
5. Erythropoietin (EPO) is a hormone that stimulates red blood cell production during hematopoiesis.

Review Questions

• What role does iron play in hematopoiesis?
• How do vitamin B12 and folate deficiencies affect hematopoiesis?
• What hormone is responsible for stimulating red blood cell production?

Related terms

Anemia:

a condition characterized by a deficiency of red blood cells or hemoglobin, often due to impaired hematopoiesis

Erythropoietin (EPO): a hormone produced by the kidneys that promotes the formation of red blood cells in the bone marrow

Bone Marrow:

the spongy tissue inside bones where hematopoiesis occurs