Histone
from class: Microbiology Definition Histones are proteins that package and order DNA into structural units called nucleosomes. They play a crucial role in gene regulation by controlling access to DNA.
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Predict what's on your test 5 Must Know Facts For Your Next Test Histones are positively charged, which helps them bind to the negatively charged DNA. There are five main types of histones: H1, H2A, H2B, H3, and H4. Histone modifications such as methylation or acetylation can influence gene expression by altering chromatin structure. During DNA replication, histones need to be duplicated along with the DNA to maintain chromatin structure. Histone proteins are highly conserved across different species, highlighting their essential role in cellular processes. Review Questions What is the primary function of histones in relation to DNA? How do histone modifications affect gene regulation? Why is it important for histones to be replicated during DNA replication?
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