Clindamycin
from class: Microbiology Definition Clindamycin is an antibiotic used to treat a variety of bacterial infections. It works by inhibiting protein synthesis in bacteria, making it effective against anaerobic bacteria and certain protozoa.
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Predict what's on your test 5 Must Know Facts For Your Next Test Clindamycin is particularly effective against Gram-positive cocci and anaerobic bacteria. It is commonly used for skin and soft tissue infections, including those caused by MRSA (Methicillin-resistant Staphylococcus aureus). Clindamycin can be administered orally, topically, or intravenously depending on the infection severity. A common side effect of clindamycin is Clostridioides difficile-associated diarrhea, which can lead to severe colitis. The drug's mechanism involves binding to the 50S ribosomal subunit, preventing bacterial protein synthesis. Review Questions What types of bacteria are most effectively treated with clindamycin? How does clindamycin inhibit bacterial growth? What is a significant gastrointestinal side effect associated with clindamycin use? "Clindamycin" also found in:
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