Oncogenes
from class: Pharmacology for Nurses Definition Oncogenes are mutated forms of genes that have the potential to cause normal cells to become cancerous. They promote cell growth and proliferation, often leading to uncontrolled cell division.
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Predict what's on your test 5 Must Know Facts For Your Next Test Oncogenes originate from proto-oncogenes, which are normal genes involved in cell growth and division. Mutations in oncogenes can be caused by various factors including radiation, chemicals, and viruses. Common examples of oncogenes include HER2, RAS, and MYC. Targeted cancer therapies often aim to inhibit the activity of specific oncogenes. Oncogenes can lead to the activation of multiple signaling pathways that contribute to tumor development. Review Questions What is the difference between a proto-oncogene and an oncogene? Name three common examples of oncogenes. How do targeted cancer therapies interact with oncogenes? "Oncogenes" also found in:
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