Monoclonal antibodies

Definition

Monoclonal antibodies are laboratory-made molecules that can bind to specific targets, such as antigens on cancer cells. They are used in various therapies, including for cancer and autoimmune diseases.

5 Must Know Facts For Your Next Test

1. Monoclonal antibodies are produced using hybridoma technology or recombinant DNA technology.
2. They can be designed to trigger the immune system to attack targeted cells.
3. Common uses include treatment of cancers, autoimmune diseases, and chronic conditions like multiple sclerosis.
4. Monoclonal antibodies can be administered via intravenous infusion or injection.
5. They often have names ending in '-mab,' which stands for monoclonal antibody.

Review Questions

• What is the primary mechanism by which monoclonal antibodies function?
• Name two diseases or conditions where monoclonal antibodies are commonly used.
• How are monoclonal antibodies typically administered to patients?

Related terms

Hybridoma Technology: A method used to produce large numbers of identical antibodies (monoclonal antibodies).

Antigens:

Molecules capable of inducing an immune response.

Immunosuppressants:

Drugs that inhibit or prevent activity of the immune system.