LDL-cholesterol

Definition

LDL-cholesterol, or low-density lipoprotein cholesterol, is often referred to as 'bad' cholesterol. High levels can lead to plaque buildup in arteries and result in cardiovascular diseases.

5 Must Know Facts For Your Next Test

1. LDL-cholesterol is a primary target for lipid-lowering therapies.
2. Statins are commonly prescribed drugs that reduce LDL-cholesterol levels.
3. High levels of LDL-cholesterol are associated with an increased risk of atherosclerosis.
4. LDL particles are responsible for transporting cholesterol from the liver to peripheral tissues.
5. Lifestyle changes such as diet and exercise can significantly impact LDL-cholesterol levels.

Review Questions

• What role does LDL-cholesterol play in cardiovascular health?
• Name two types of medications used to lower LDL-cholesterol levels.
• How can lifestyle modifications impact LDL-cholesterol?

Related terms

HDL-cholesterol:

High-density lipoprotein cholesterol, known as 'good' cholesterol, which helps remove other forms of cholesterol from the bloodstream.

Statins:

A class of drugs used to lower blood cholesterol levels by inhibiting the enzyme HMG-CoA reductase.

Apolipoproteins: Protein components of lipoproteins that serve structural roles and help regulate lipid metabolism.