Children

Definition

Children are individuals in the developmental stage between infancy and adolescence. Their physiological and psychological characteristics impact how they respond to various pharmacological treatments.

5 Must Know Facts For Your Next Test

1. Children's metabolic rates can be higher than adults, affecting drug absorption and elimination.
2. Dosing for children often requires careful calculation based on weight or surface area.
3. Pediatric patients may have different side effect profiles compared to adults when using the same medication.
4. Off-label drug use is common in pediatric pharmacology due to limited clinical trials specifically involving children.
5. Developmental changes in organ function, such as liver maturation, play a crucial role in drug metabolism for children.

Review Questions

• Why is it important to calculate drug dosages based on weight or surface area in children?
• How do metabolic rates in children affect their response to medications?
• What are some challenges associated with off-label drug use in pediatric patients?

Related terms

Metabolism:

The biochemical process of breaking down substances within the body, impacting how drugs are processed.

Dosage Calculation:

The method of determining the appropriate amount of medication for administration based on factors like age, weight, and surface area.

Off-Label Use:

The prescription of drugs for an age group or condition that is not officially approved by regulatory agencies.