Proteobacteria

Definition

Proteobacteria are a major phylum of Gram-negative bacteria that include a wide variety of pathogens. They play significant roles in the gastrointestinal system's health and disease states.

5 Must Know Facts For Your Next Test

1. Proteobacteria can influence gut health by interacting with the host's immune system.
2. Certain Proteobacteria species are involved in the development of gastrointestinal diseases such as Crohn's disease and ulcerative colitis.
3. Dietary factors, like high-fat diets, can increase the abundance of Proteobacteria in the gut.
4. Probiotics and prebiotics can modulate the levels of Proteobacteria to promote a healthy gut microbiota.
5. An imbalance in Proteobacteria is often associated with dysbiosis, which can lead to digestive issues and inflammation.

Review Questions

• How do Proteobacteria interact with the host’s immune system to influence gut health?
• Which gastrointestinal diseases have been linked to certain species of Proteobacteria?
• What dietary factors can affect the abundance of Proteobacteria in the gut?

Related terms

Microbiota:

The community of microorganisms, including bacteria, fungi, and viruses, that inhabit a particular environment such as the human gut.

Dysbiosis:

An imbalance in the microbial communities within the body, often associated with disease or adverse conditions.

Probiotics:

Live beneficial bacteria that are taken as supplements or found in certain foods to help maintain or restore healthy gut microbiota.