Peptic ulcer disease

Definition

Peptic ulcer disease (PUD) involves the formation of sores or ulcers in the lining of the stomach, small intestine, or esophagus. It is often caused by infection with Helicobacter pylori bacteria or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs).

5 Must Know Facts For Your Next Test

1. Helicobacter pylori infection is a major cause of peptic ulcer disease.
2. Prolonged use of NSAIDs can lead to the development of peptic ulcers.
3. Symptoms include burning stomach pain, bloating, and nausea.
4. Complications from untreated peptic ulcers can include bleeding, perforation, and gastric obstruction.
5. Treatment options often involve antibiotics to eradicate H. pylori and medications to reduce stomach acid.

Review Questions

• What are the two primary causes of peptic ulcer disease?
• What are common symptoms associated with peptic ulcer disease?
• Which complications can arise if a peptic ulcer is left untreated?

Related terms

Gastritis: Inflammation of the stomach lining that can be caused by various factors including alcohol use, chronic vomiting, stress, or certain medications.

Helicobacter_pylori: A type of bacteria that infects the stomach and is a common cause of peptic ulcers.

NSAIDs: Nonsteroidal anti-inflammatory drugs that can cause irritation and damage to the gastrointestinal tract lining with prolonged use.