Glomerular filtration rate (GFR)

Definition

Glomerular Filtration Rate (GFR) measures how well the kidneys filter blood, indicating overall kidney function. It is expressed in milliliters per minute and is crucial for assessing renal health.

5 Must Know Facts For Your Next Test

1. GFR is influenced by factors such as age, gender, body size, and race.
2. Normal GFR ranges from 90 to 120 mL/min/1.73 m² in healthy adults.
3. A low GFR can indicate chronic kidney disease (CKD) or acute kidney injury (AKI).
4. Nutrition, particularly protein intake, can significantly affect GFR and overall renal health.
5. GFR calculations often use equations like the CKD-EPI formula to estimate kidney function.

Review Questions

• What does a low GFR indicate about kidney function?
• How can nutrition impact GFR levels?
• Which factors are considered when calculating GFR?

Related terms

Creatinine:

A waste product measured in the blood that helps estimate GFR and assess kidney function.

Chronic Kidney Disease (CKD): A long-term condition where the kidneys do not work as well as they should.

Proteinuria:

The presence of excess protein in urine, often a sign of kidney damage or disease.