Ghrelin

Definition

Ghrelin is a hormone produced mainly by the stomach, which stimulates appetite and promotes fat storage. It plays a significant role in regulating energy balance and metabolism.

5 Must Know Facts For Your Next Test

1. Ghrelin levels increase before meals and decrease after eating.
2. It is often referred to as the 'hunger hormone' due to its role in signaling hunger to the brain.
3. Ghrelin interacts with receptors in the hypothalamus to stimulate appetite.
4. Chronic stress can elevate ghrelin levels, leading to increased food intake and weight gain.
5. Sleep deprivation has been shown to raise ghrelin levels, potentially contributing to overeating.

Review Questions

• What primary function does ghrelin serve in the body?
• How do ghrelin levels change in relation to meal times?
• What impact does sleep deprivation have on ghrelin levels?

Related terms

Leptin:

A hormone produced by adipose (fat) tissue that helps regulate energy balance by inhibiting hunger.

Insulin:

A hormone produced by the pancreas that regulates blood glucose levels by facilitating cellular uptake of glucose.

Hypothalamus:

A region of the brain that controls several endocrine functions, including hunger and thirst regulation.