T cells are a type of lymphocyte that play a central role in cell-mediated immunity. They are characterized by the presence of T-cell receptors (TCR) on their surface.
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T cells originate in the bone marrow but mature in the thymus.
There are two main types of T cells: Helper T cells (CD4+) and Cytotoxic T cells (CD8+).
Helper T cells assist other white blood cells in immunologic processes, including the activation of B cells to secrete antibodies.
Cytotoxic T cells directly kill infected or cancerous cells by inducing apoptosis.
T-cell receptors (TCRs) recognize antigens presented by Major Histocompatibility Complex (MHC) molecules.
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Related terms
Lymphocyte: A type of white blood cell involved in the adaptive immune response.
B Cell: A type of lymphocyte responsible for producing antibodies.