Stationary phase

Definition

The stationary phase is a period in the microbial growth curve where the rate of cell growth equals the rate of cell death. This results in a plateau in the number of viable cells.

5 Must Know Facts For Your Next Test

1. During the stationary phase, nutrient depletion and waste accumulation limit further population growth.
2. Cells may enter a state of metabolic dormancy to survive harsh conditions during this phase.
3. Secondary metabolites, such as antibiotics, are often produced during the stationary phase.
4. The stationary phase follows the exponential (log) phase and precedes the death phase in the microbial growth curve.
5. Changes in gene expression occur as microbes adapt to stress conditions in this phase.

Review Questions

• What factors contribute to cells entering the stationary phase?
• How does cell metabolism change during the stationary phase?
• What types of compounds are commonly produced by microbes during the stationary phase?

Related terms

Lag Phase:

The initial phase of microbial growth where cells adapt to new environmental conditions and no significant increase in cell number occurs.

Exponential Phase:

A period of rapid cell division and population growth where nutrient availability is high.

Death Phase:

The final stage of microbial growth characterized by a decline in viable cell numbers due to adverse conditions and nutrient depletion.