Serotonin

Definition

Serotonin is a neurotransmitter that plays a key role in regulating mood, appetite, and sleep. It also influences various physiological functions in the immune system.

5 Must Know Facts For Your Next Test

1. Serotonin can modulate immune responses and has been implicated in hypersensitivity reactions.
2. It is synthesized from the amino acid tryptophan and stored in platelets within the bloodstream.
3. Increased levels of serotonin are associated with certain allergic reactions and anaphylaxis.
4. Serotonin receptors are found on various immune cells, including T-cells and macrophages.
5. Blocking serotonin pathways can potentially reduce symptoms of hypersensitivities.

Review Questions

• How does serotonin influence hypersensitivity reactions?
• What role do platelets play in serotonin storage?
• Which immune cells have receptors for serotonin?

Related terms

Neurotransmitter: Chemicals that transmit signals across synapses between neurons.

Tryptophan: An essential amino acid used by the body to synthesize serotonin.

Anaphylaxis:

A severe, potentially life-threatening allergic reaction characterized by rapid onset.