Goblet cells

Definition

Goblet cells are specialized epithelial cells that secrete mucus to protect mucous membranes. They play a critical role in trapping pathogens and particles, preventing them from entering the body.

5 Must Know Facts For Your Next Test

1. Goblet cells are found in the respiratory and gastrointestinal tracts.
2. They secrete mucus composed mainly of mucins, which are glycoproteins that provide a gel-like consistency.
3. The mucus produced by goblet cells traps microbes and debris, facilitating their removal through ciliary action or peristalsis.
4. Goblet cell secretion is an innate defense mechanism that helps prevent infections by creating a physical barrier.
5. They are named for their characteristic goblet-like shape, which is due to the accumulation of mucin granules.

Review Questions

• Where in the body are goblet cells typically found?
• What is the primary function of mucus secreted by goblet cells?
• How do goblet cells contribute to innate nonspecific host defenses?

Related terms

Mucins: Glycoproteins that give mucus its gel-like consistency.

Cilia:

Hair-like structures on epithelial cells that move mucus along surfaces.

Epithelial Cells: Cells forming the lining of internal and external surfaces of the body.