Edward Jenner

Definition

Edward Jenner was an English physician and scientist who pioneered the concept of vaccines, particularly for smallpox. His work laid the groundwork for modern immunology.

5 Must Know Facts For Your Next Test

1. Edward Jenner developed the first successful smallpox vaccine in 1796 using material from cowpox lesions.
2. Jenner's method involved inoculating individuals with cowpox to confer immunity to smallpox.
3. He is often referred to as the 'Father of Immunology' because his work led to the development of vaccines for various diseases.
4. Jenner's experiments demonstrated that exposure to a less virulent pathogen could provide protection against a more deadly one, a principle known as cross-immunity.
5. The term 'vaccine' itself is derived from 'Variolae vaccinae' (smallpox of the cow), which Jenner used in his research.

Review Questions

• What disease did Edward Jenner develop a vaccine for?
• How did Edward Jenner's discovery contribute to modern immunology?
• Why is Edward Jenner called the 'Father of Immunology'?

Related terms

Vaccine: A biological preparation that provides active acquired immunity to a particular infectious disease.

Smallpox:

A contagious and sometimes fatal infectious disease caused by the variola virus, eradicated by global vaccination efforts.

Cross-immunity: Immunity to one pathogen due to exposure or vaccination with a different but related pathogen.