Desquamation

Definition

Desquamation is the shedding or peeling of the outermost layer of the skin, known as the stratum corneum. This process plays a crucial role in maintaining healthy skin by removing dead cells and allowing for regeneration.

5 Must Know Facts For Your Next Test

1. Desquamation helps prevent pathogens from colonizing on the skin by continuously shedding potential contaminants.
2. The process is influenced by various factors, including environmental conditions, age, and underlying health conditions.
3. Disorders such as psoriasis and eczema can disrupt normal desquamation, leading to scaling and flaking.
4. Certain infections, like Staphylococcus aureus, can affect desquamation by either accelerating or inhibiting the shedding process.
5. The normal microbiota of the skin can influence desquamation through interactions with keratinocytes.

Review Questions

• What is desquamation and why is it important for skin health?
• How does desquamation help protect against infections?
• Name two disorders that can disrupt normal desquamation.

Related terms

Stratum Corneum:

The outermost layer of the epidermis consisting of dead cells that are routinely shed.

Keratinocytes:

Cells found in the epidermis that produce keratin and play a key role in forming barriers against environmental damage.

Microbiota:

The community of microorganisms living on or within various body sites, including the skin.