Chain

Definition

Ernst Chain was a German-born British biochemist who, along with Howard Florey, played a crucial role in the development and mass production of penicillin. His contributions to the field of antibiotics were instrumental in advancing chemotherapy.

5 Must Know Facts For Your Next Test

1. Ernst Chain shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Alexander Fleming.
2. Chain's research significantly improved the extraction and purification process of penicillin.
3. He helped demonstrate penicillin's efficacy against bacterial infections through rigorous clinical trials.
4. Chain's work laid foundational principles for modern antibiotic treatment and drug development.
5. Despite his significant contributions, Chain initially faced skepticism and funding challenges.

Review Questions

• What role did Ernst Chain play in the development of penicillin?
• With whom did Ernst Chain share the Nobel Prize in Physiology or Medicine in 1945?
• How did Ernst Chain contribute to the field of antimicrobial drugs?

Related terms

Antibiotic: A substance used to kill or inhibit bacterial growth.

Chemotherapy:

The use of chemical substances to treat disease, particularly cancer and infections.

Penicillin:

The first antibiotic discovered by Alexander Fleming, later developed for mass production by Florey and Chain.