Aspergillosis

Definition

Aspergillosis is an infection caused by the Aspergillus species of fungi, which primarily affects the respiratory system but can disseminate to other organs. It is most commonly seen in immunocompromised individuals.

5 Must Know Facts For Your Next Test

1. Aspergillosis is caused by inhalation of Aspergillus spores.
2. Common forms include allergic bronchopulmonary aspergillosis, chronic pulmonary aspergillosis, and invasive aspergillosis.
3. Invasive aspergillosis can lead to severe complications in immunocompromised patients, such as those undergoing chemotherapy or organ transplants.
4. Diagnosis typically involves imaging studies like CT scans and laboratory tests including culture and PCR for fungal DNA.
5. Treatment often includes antifungal drugs like voriconazole or amphotericin B.

Review Questions

• What are the primary risk factors for developing invasive aspergillosis?
• How is aspergillosis diagnosed in a clinical setting?
• Which antifungal drugs are commonly used to treat aspergillosis?

Related terms

Antifungal Drugs: Medications used to treat fungal infections by targeting specific components of fungal cells.

Virulence Factors:

Molecules produced by pathogens that contribute to their ability to cause disease.

Mycoses: Infections caused by fungi, which can affect various parts of the body including skin, nails, and lungs.