An activator is a protein that increases gene transcription by binding to an enhancer or promoter-proximal element. Activators facilitate the binding of RNA polymerase to the promoter, initiating transcription.
5 Must Know Facts For Your Next Test
Activators bind to specific DNA sequences known as enhancers or promoter-proximal elements.
They play a crucial role in positive regulation of gene expression.
The interaction between activators and RNA polymerase enhances the rate of transcription initiation.
Some activators require co-activators to function effectively.
Mutations in activator proteins can lead to dysregulation of gene expression and associated diseases.