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from class: Microbiology Definition The ABO blood group system classifies human blood based on the presence or absence of antigens A and B on red blood cells. This system is crucial in transfusion medicine and can trigger immune responses if incompatible blood types are mixed.
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Predict what's on your test 5 Must Know Facts For Your Next Test The four main ABO blood groups are A, B, AB, and O. Type O blood lacks both A and B antigens but has anti-A and anti-B antibodies, making it a universal donor. Type AB blood has both A and B antigens but lacks antibodies against them, making it a universal recipient. Incompatible blood transfusions can cause severe immune reactions due to antibody-mediated destruction of red blood cells. The ABO system is genetically determined by the inheritance of alleles from parents. Review Questions What are the four main ABO blood groups? Why is type O considered a universal donor? What can happen if incompatible ABO blood types are mixed during a transfusion?
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