Intro to Pharmacology

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Zinc

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Intro to Pharmacology

Definition

Zinc is an essential trace mineral that plays a crucial role in various biological functions, including enzyme activity, immune system support, and protein synthesis. This mineral is vital for maintaining overall health and is found in many foods, as well as available in dietary supplements.

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5 Must Know Facts For Your Next Test

  1. Zinc is involved in over 300 enzymatic reactions in the body, making it crucial for metabolism and digestion.
  2. The recommended dietary allowance (RDA) for zinc varies by age and gender, with adult men needing about 11 mg per day and adult women about 8 mg per day.
  3. Good dietary sources of zinc include meat, shellfish, legumes, seeds, nuts, dairy products, and whole grains.
  4. Zinc absorption can be inhibited by phytates found in plant-based foods, which means vegetarians and vegans may need to pay extra attention to their zinc intake.
  5. Excessive zinc intake can lead to toxicity, resulting in symptoms like nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches.

Review Questions

  • How does zinc contribute to immune system function and why is it particularly important during illness?
    • Zinc plays a vital role in the immune system by supporting the development and function of immune cells such as T-lymphocytes and macrophages. It helps regulate immune responses and has been shown to reduce the duration and severity of common colds. During illness, the body's demand for zinc increases due to its role in fighting infections, making adequate intake essential for recovery.
  • Discuss the potential effects of zinc deficiency on growth and development in children.
    • Zinc deficiency can significantly impact growth and development in children, leading to stunted growth and delayed sexual maturation. It also compromises the immune system, increasing susceptibility to infections which can further impede healthy development. Ensuring adequate zinc intake during childhood is crucial for proper physical and cognitive development.
  • Evaluate the implications of bioavailability on dietary zinc sources for different populations, such as vegetarians compared to meat-eaters.
    • Bioavailability of zinc varies significantly between animal-based and plant-based sources due to the presence of phytates in plant foods that inhibit absorption. For vegetarians, this means they may need to consume more zinc-rich foods or consider supplements to meet their needs effectively. In contrast, meat-eaters typically absorb zinc more efficiently from their diets. Understanding these differences is essential for ensuring all populations achieve sufficient zinc levels for optimal health.
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