Intro to Computational Biology
The branch-and-bound method is an algorithmic approach used for solving optimization problems by systematically exploring the solution space. It divides the problem into smaller subproblems (branching) and eliminates suboptimal solutions based on bounds to find the best solution efficiently. This method is particularly useful in finding optimal solutions for problems like maximum parsimony in phylogenetic analysis, where one seeks to minimize the total cost of character changes across a phylogenetic tree.
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