key term - Overdose

Definition

An overdose occurs when a person takes an excessive amount of a substance, usually a drug, which leads to severe and life-threatening complications. In the context of substance use and abuse, an overdose can result in dangerous physical and psychological symptoms that require immediate medical attention.

5 Must Know Facts For Your Next Test

1. Overdoses can occur with both legal and illegal substances, including prescription medications, alcohol, and illicit drugs.
2. Risk factors for overdose include high-dose use, mixing substances, and underlying medical conditions that impair the body's ability to metabolize drugs.
3. Symptoms of an overdose can include slowed breathing, loss of consciousness, seizures, and in severe cases, coma and death.
4. Immediate medical intervention, such as the administration of naloxone, can often reverse the effects of an opioid overdose and save a person's life.
5. Overdose prevention strategies include education, access to harm reduction services, and the development of effective treatment options for substance use disorders.

Review Questions

• Explain how tolerance can contribute to the risk of an overdose.
  • Tolerance occurs when a person's body becomes accustomed to a substance, requiring higher doses to achieve the same effect. This can be particularly dangerous with opioids, as the user may take an amount they previously tolerated, only to find that it has become a lethal overdose due to their increased tolerance. The body's ability to metabolize the drug may not have kept pace with the user's need for higher doses, leading to a potentially fatal overdose.
• Describe the role of withdrawal in the context of an overdose.
  • Withdrawal symptoms can be a significant factor in the risk of an overdose. When a person who is dependent on a substance suddenly stops using it, they may experience intense cravings and physical symptoms that drive them to quickly re-use the substance at high doses in an attempt to alleviate the withdrawal. This sudden, high-dose use can easily lead to an overdose, as the body is no longer accustomed to handling such a large amount of the substance.
• Analyze how substance abuse disorders can increase the likelihood of an overdose.
  • Substance abuse disorders are characterized by a compulsive need to use a substance, despite the harmful consequences. This can lead to a person continuing to use increasingly larger doses of a substance, even as their tolerance increases and the risk of overdose grows. Additionally, individuals with substance abuse disorders may be more likely to engage in risky behaviors, such as mixing multiple substances, which further heightens the danger of an overdose. Addressing the underlying substance abuse disorder through comprehensive treatment is crucial in reducing the risk of a potentially fatal overdose.

Related terms

Tolerance:

The decreased response to a substance that occurs with repeated use, requiring higher doses to achieve the same effect.

Withdrawal:

The physical and psychological symptoms that occur when a person stops using a substance they have become dependent on.

Substance Abuse Disorder: A chronic, relapsing condition characterized by compulsive drug seeking and use, despite harmful consequences.