Autoimmunity

Definition

Autoimmunity is a condition where the immune system mistakenly attacks the body's own cells and tissues. This can lead to various autoimmune diseases, characterized by chronic inflammation and tissue damage.

5 Must Know Facts For Your Next Test

1. Autoimmune diseases are caused by failure in immune tolerance.
2. Common examples of autoimmune diseases include rheumatoid arthritis, lupus, and type 1 diabetes.
3. Genetic factors can predispose individuals to autoimmunity.
4. Environmental triggers like infections or toxins may initiate autoimmune responses.
5. Diagnosis often involves detecting specific autoantibodies in the blood.

Review Questions

• What is autoimmunity?
• Name two common autoimmune diseases.
• How can genetic factors influence autoimmunity?

Related terms

Immune Tolerance: The ability of the immune system to recognize self-antigens and not mount an attack against them.

Autoantibodies:

Antibodies produced by the immune system that target the body's own tissues.

Chronic Inflammation: Long-term inflammation that can result from persistent immune responses, including those seen in autoimmune diseases.