Neural tube

Definition

The neural tube is an embryonic structure that forms the brain and spinal cord. It arises during early development from the folding of the neural plate in vertebrates.

5 Must Know Facts For Your Next Test

1. The neural tube closure is a critical step in the process known as neurulation.
2. Failure in neural tube closure can result in birth defects such as spina bifida and anencephaly.
3. The neural tube forms by the 4th week of embryonic development in humans.
4. Neural crest cells, which give rise to diverse cell types, originate from the edges of the neural tube.
5. Sonic hedgehog (Shh) signaling plays a crucial role in the patterning of the neural tube.

Review Questions

• What structure does the neural tube eventually form?
• What are two major birth defects associated with improper neural tube closure?
• During which week of human embryonic development does the neural tube typically form?

Related terms

Neurulation:

The process during embryonic development where the neural plate folds to form the neural tube.

Neural Crest Cells: Cells that emerge from the edge of the neural tube and migrate to form various tissues and structures.

Sonic Hedgehog (Shh): A protein that provides essential signals for developmental processes including patterning of the neural tube.