Cholecystokinin

Definition

Cholecystokinin (CCK) is a hormone produced in the small intestine that stimulates the digestion of fats and proteins. It also triggers the release of digestive enzymes from the pancreas and bile from the gallbladder.

5 Must Know Facts For Your Next Test

1. CCK is released by cells in the duodenum in response to the presence of chyme.
2. It enhances digestion by slowing gastric emptying and promoting satiety.
3. CCK stimulates the gallbladder to contract and release stored bile into the intestine.
4. It prompts the pancreas to secrete its digestive enzymes, such as trypsin and lipase.
5. CCK also acts on the brain to produce a feeling of fullness after eating.

Review Questions

• What triggers the release of cholecystokinin?
• How does CCK influence pancreatic enzyme secretion?
• In what way does CCK contribute to feelings of satiety?

Related terms

Gastrin:

A hormone that stimulates secretion of gastric acid by the stomach.

Secretin:

A hormone that stimulates bicarbonate production in the pancreas to neutralize stomach acid.

Bile:

A digestive fluid produced by the liver and stored in the gallbladder, essential for fat digestion.