Calcitonin is a hormone produced by the thyroid gland that helps regulate blood calcium levels. It lowers blood calcium by inhibiting osteoclast activity and promoting calcium excretion in the kidneys.
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Calcitonin is secreted by the parafollicular cells (C-cells) of the thyroid gland.
The primary action of calcitonin is to decrease blood calcium levels.
Calcitonin inhibits osteoclasts, which are cells that break down bone tissue.
It promotes renal excretion of calcium and phosphate, reducing their levels in the bloodstream.
Calcitonin's effects are generally opposite to those of parathyroid hormone (PTH).
Review Questions
Which gland produces calcitonin?
What is the main function of calcitonin in regulating calcium levels?
How does calcitonin affect osteoclast activity?
Related terms
Parathyroid Hormone (PTH): A hormone released by the parathyroid glands that increases blood calcium levels by stimulating osteoclast activity and decreasing renal excretion of calcium.