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Disaccharide

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Biological Chemistry I

Definition

A disaccharide is a type of carbohydrate formed from the chemical bonding of two monosaccharides, resulting in a sugar with a general formula of C$_{12}$H$_{22}$O$_{11}$. Disaccharides play important roles in energy storage and transport within living organisms, and their structure can influence their digestibility and biological function.

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5 Must Know Facts For Your Next Test

  1. Common examples of disaccharides include sucrose (table sugar), lactose (milk sugar), and maltose (malt sugar), each made up of different combinations of monosaccharides.
  2. Disaccharides can be broken down into their monosaccharide components through hydrolysis, a reaction that requires water and is catalyzed by enzymes.
  3. The structural configuration of disaccharides can lead to different properties; for example, sucrose is non-reducing while maltose is reducing due to the availability of free aldehyde or ketone groups.
  4. Disaccharides are important sources of energy for organisms; they are often found in foods and can be quickly utilized by the body after digestion.
  5. The classification of disaccharides as reducing or non-reducing is based on whether they can act as reducing agents in biochemical reactions, which affects their role in metabolism.

Review Questions

  • How does the formation of a glycosidic bond influence the properties and function of disaccharides?
    • The formation of a glycosidic bond between two monosaccharides during the synthesis of disaccharides creates a unique molecular structure that influences its properties, such as solubility and reactivity. For example, the specific type of glycosidic linkage can determine if the disaccharide is reducing or non-reducing, which impacts its biological functions. Understanding these bonds helps in studying how disaccharides are metabolized and utilized for energy within organisms.
  • Compare and contrast sucrose and lactose in terms of their composition, properties, and biological significance.
    • Sucrose is composed of glucose and fructose linked by an α-1,2-glycosidic bond, making it a non-reducing sugar primarily found in plants as an energy source. In contrast, lactose consists of glucose and galactose linked by a β-1,4-glycosidic bond and serves as the primary sugar in milk, being a significant energy source for infants. The differences in their composition affect their digestibility; lactose requires the enzyme lactase for hydrolysis, while sucrose can be directly broken down by sucrase.
  • Evaluate the role of disaccharides in human nutrition and their impact on health.
    • Disaccharides are essential in human nutrition as they provide a quick source of energy when consumed. However, excessive intake can lead to health issues like obesity and diabetes due to rapid spikes in blood sugar levels. Understanding the digestion and metabolism of disaccharides allows for better dietary choices, such as balancing their consumption with fiber-rich foods to mitigate negative health impacts while still benefiting from their energy-providing properties.
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