AP US History
Diseases refer to illnesses caused by pathogens, such as bacteria and viruses, which can spread through contact, contaminated water, or other means. The introduction of new diseases during the age of exploration had devastating effects on indigenous populations in the Americas, as they lacked immunity to these foreign pathogens. This played a critical role in shaping the interactions among Europeans, Native Americans, and Africans as societies changed dramatically due to population declines and shifting power dynamics.