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Silencers are regions on DNA that decrease or prevent the expression (transcription) of certain genes when binding with particular proteins known as repressors.
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Proteins that inhibit the expression of one or more genes by binding to the operator or associated silencers.
Downstream: Refers to the direction in which genetic information is transcribed from DNA to RNA.
Substances that slow down or stop a chemical reaction, in this case, they can prevent gene expression.