Secretin

Definition

Secretin is a hormone produced by the S cells of the duodenum that stimulates the pancreas to release bicarbonate-rich fluids, essential for neutralizing stomach acid in the small intestine and aiding in protein digestion. It plays a pivotal role in regulating the pH of the intestinal environment to optimize enzyme activity for nutrient absorption.

Related terms

Pancreas: An organ that produces digestive enzymes and hormones, including insulin and glucagon, which regulate blood sugar levels.

Duodenum:

The first section of the small intestine immediately beyond the stomach, where most chemical digestion occurs.

Bicarbonate:

A base that neutralizes stomach acid, allowing for proper digestion and absorption of nutrients in the small intestine