Holocrine secretion

Definition

Holocrine secretion is a process by which secretory cells accumulate a product and then release it through the rupture and destruction of the cell. This mode of secretion involves the entire cell becoming packed with secretory products until it bursts, releasing its contents.

Related terms

Sebaceous glands: These are exocrine glands in the skin that secrete oils (sebum) through holocrine secretion to lubricate skin and hair.

Apocrine secretion: This is a mode of secretion where parts of cytoplasm are pinched off with the secretory product, unlike holocrine secretion where the whole cell disintegrates.

Exocrine glands: Glands that release their secretions onto an epithelial surface directly or through ducts, including those utilizing holocrine secretion